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Neural network learning defines glioblastoma features to be of neural crest perivascular or radial glia lineages

Glioblastoma is believed to originate from nervous system cells; however, a putative origin from vessel-associated progenitor cells has not been considered. We deeply single-cell RNA–sequenced glioblastoma progenitor cells of 18 patients and integrated 710 bulk tumors and 73,495 glioma single cells...

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Detalles Bibliográficos
Autores principales: Hu, Yizhou, Jiang, Yiwen, Behnan, Jinan, Ribeiro, Mariana Messias, Kalantzi, Chrysoula, Zhang, Ming-Dong, Lou, Daohua, Häring, Martin, Sharma, Nilesh, Okawa, Satoshi, Del Sol, Antonio, Adameyko, Igor, Svensson, Mikael, Persson, Oscar, Ernfors, Patrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177076/
https://www.ncbi.nlm.nih.gov/pubmed/35675414
http://dx.doi.org/10.1126/sciadv.abm6340