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Signaling Downstream of Focal Adhesions Regulates Stiffness-Dependent Differences in the TGF-β1-Mediated Myofibroblast Differentiation of Corneal Keratocytes
Following injury and refractive surgery, corneal wound healing can initiate a protracted fibrotic response that interferes with ocular function. This fibrosis is related, in part, to the myofibroblast differentiation of corneal keratocytes in response to transforming growth factor beta 1 (TGF-β1). P...
Autores principales: | Maruri, Daniel P., Iyer, Krithika S., Schmidtke, David W., Petroll, W. Matthew, Varner, Victor D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177138/ https://www.ncbi.nlm.nih.gov/pubmed/35693927 http://dx.doi.org/10.3389/fcell.2022.886759 |
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