T cells discriminate between groups C1 and C2 HLA-C

Dimorphic amino acids at positions 77 and 80 delineate HLA-C allotypes into two groups, C1 and C2, which associate with disease through interactions with C1 and C2-specific natural killer cell receptors. How the C1/C2 dimorphism affects T cell recognition is unknown. Using HLA-C allotypes that diffe...

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Detalles Bibliográficos
Autores principales: Sim, Malcolm J W, Stotz, Zachary, Lu, Jinghua, Brennan, Paul, Long, Eric O, Sun, Peter D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177145/
https://www.ncbi.nlm.nih.gov/pubmed/35587797
http://dx.doi.org/10.7554/eLife.75670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177145/
https://www.ncbi.nlm.nih.gov/pubmed/35587797
http://dx.doi.org/10.7554/eLife.75670

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