Cryo-sensitive aggregation triggers NLRP3 inflammasome assembly in cryopyrin-associated periodic syndrome

Cryopyrin-associated periodic syndrome (CAPS) is an autoinflammatory syndrome caused by mutations of NLRP3 gene encoding cryopyrin. Familial cold autoinflammatory syndrome, the mildest form of CAPS, is characterized by cold-induced inflammation induced by the overproduction of IL-1β. However, the mo...

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Detalles Bibliográficos
Autores principales: Karasawa, Tadayoshi, Komada, Takanori, Yamada, Naoya, Aizawa, Emi, Mizushina, Yoshiko, Watanabe, Sachiko, Baatarjav, Chintogtokh, Matsumura, Takayoshi, Takahashi, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177154/
https://www.ncbi.nlm.nih.gov/pubmed/35616535
http://dx.doi.org/10.7554/eLife.75166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177154/
https://www.ncbi.nlm.nih.gov/pubmed/35616535
http://dx.doi.org/10.7554/eLife.75166

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