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Renal cancer stem cell-derived sEVs impair renal function by inducing renal cell ERS and apoptosis in mice

BACKGROUND: Cancer stem cells (CSCs) have been confirmed to participate in tumorigenesis, development, and metastasis, and to affect the local environment in normal tissues. Extracellular vesicles derived from CSCs (CSC-EVs) affect the local environment, contributing to tumor metastasis. However, th...

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Detalles Bibliográficos
Autores principales: Wu, Ruoyu, Chen, Zhiguo, Ma, Junjie, Huang, Wenjie, Wu, Ke, Chen, Yang, Zheng, Junhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177253/
https://www.ncbi.nlm.nih.gov/pubmed/35693719
http://dx.doi.org/10.21037/tau-21-1007