Protective Effects of Amauroderma rugosum on Doxorubicin-Induced Cardiotoxicity through Suppressing Oxidative Stress, Mitochondrial Dysfunction, Apoptosis, and Activating Akt/mTOR and Nrf2/HO-1 Signaling Pathways

Clinical outcomes for doxorubicin (Dox) are limited by its cardiotoxicity but a combination of Dox and agents with cardioprotective activities is an effective strategy to improve its therapeutic outcome. Natural products provide abundant resources to search for novel cardioprotective agents. Ganoder...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jingjing, Cheng, Yanfen, Li, Renkai, Wu, Xiaoping, Zheng, Chengwen, Shiu, Polly Ho-Ting, Chan, Jacqueline Cho-Ki, Rangsinth, Panthakarn, Liu, Conghui, Leung, Susan Wai-Sum, Lee, Simon Ming-Yuen, Zhang, Chen, Fu, Chaomei, Zhang, Jinming, Cheung, Timothy Man-Yau, Leung, George Pak-Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177334/
https://www.ncbi.nlm.nih.gov/pubmed/35693699
http://dx.doi.org/10.1155/2022/9266178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177334/
https://www.ncbi.nlm.nih.gov/pubmed/35693699
http://dx.doi.org/10.1155/2022/9266178

Ejemplares similares