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Protective Effects of Amauroderma rugosum on Doxorubicin-Induced Cardiotoxicity through Suppressing Oxidative Stress, Mitochondrial Dysfunction, Apoptosis, and Activating Akt/mTOR and Nrf2/HO-1 Signaling Pathways
Clinical outcomes for doxorubicin (Dox) are limited by its cardiotoxicity but a combination of Dox and agents with cardioprotective activities is an effective strategy to improve its therapeutic outcome. Natural products provide abundant resources to search for novel cardioprotective agents. Ganoder...
Autores principales: | Li, Jingjing, Cheng, Yanfen, Li, Renkai, Wu, Xiaoping, Zheng, Chengwen, Shiu, Polly Ho-Ting, Chan, Jacqueline Cho-Ki, Rangsinth, Panthakarn, Liu, Conghui, Leung, Susan Wai-Sum, Lee, Simon Ming-Yuen, Zhang, Chen, Fu, Chaomei, Zhang, Jinming, Cheung, Timothy Man-Yau, Leung, George Pak-Heng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177334/ https://www.ncbi.nlm.nih.gov/pubmed/35693699 http://dx.doi.org/10.1155/2022/9266178 |
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