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Protective Effects of Amauroderma rugosum on Doxorubicin-Induced Cardiotoxicity through Suppressing Oxidative Stress, Mitochondrial Dysfunction, Apoptosis, and Activating Akt/mTOR and Nrf2/HO-1 Signaling Pathways

Clinical outcomes for doxorubicin (Dox) are limited by its cardiotoxicity but a combination of Dox and agents with cardioprotective activities is an effective strategy to improve its therapeutic outcome. Natural products provide abundant resources to search for novel cardioprotective agents. Ganoder...

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Detalles Bibliográficos
Autores principales: Li, Jingjing, Cheng, Yanfen, Li, Renkai, Wu, Xiaoping, Zheng, Chengwen, Shiu, Polly Ho-Ting, Chan, Jacqueline Cho-Ki, Rangsinth, Panthakarn, Liu, Conghui, Leung, Susan Wai-Sum, Lee, Simon Ming-Yuen, Zhang, Chen, Fu, Chaomei, Zhang, Jinming, Cheung, Timothy Man-Yau, Leung, George Pak-Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177334/
https://www.ncbi.nlm.nih.gov/pubmed/35693699
http://dx.doi.org/10.1155/2022/9266178

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