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The longitudinal dynamics and natural history of clonal haematopoiesis

Clonal expansions driven by somatic mutations become pervasive across human tissues with age, including in the haematopoietic system, where the phenomenon is termed clonal haematopoiesis(1–4). The understanding of how and when clonal haematopoiesis develops, the factors that govern its behaviour, ho...

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Detalles Bibliográficos
Autores principales: Fabre, Margarete A., de Almeida, José Guilherme, Fiorillo, Edoardo, Mitchell, Emily, Damaskou, Aristi, Rak, Justyna, Orrù, Valeria, Marongiu, Michele, Chapman, Michael Spencer, Vijayabaskar, M. S., Baxter, Joanna, Hardy, Claire, Abascal, Federico, Williams, Nicholas, Nangalia, Jyoti, Martincorena, Iñigo, Campbell, Peter J., McKinney, Eoin F., Cucca, Francesco, Gerstung, Moritz, Vassiliou, George S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177423/
https://www.ncbi.nlm.nih.gov/pubmed/35650444
http://dx.doi.org/10.1038/s41586-022-04785-z