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Methoxybenzamide derivative of nimesulide from anti-fever to anti-cancer: Chemical characterization and cytotoxicity

The repurposing strategy of converting nimesulide from an anti-fever drug to an anti-cancer agent by modifying its main structure targeting HSP27 is gaining great attention these days. The goal of this study focuses on synthesizing a new nimesulide derivative with new ligands that have biological an...

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Detalles Bibliográficos
Autores principales: Jaragh-Alhadad, Laila A., Ali, Mayada S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177461/
https://www.ncbi.nlm.nih.gov/pubmed/35693435
http://dx.doi.org/10.1016/j.jsps.2022.03.004