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Nondestructive cellular-level 3D observation of mouse kidney using laboratory-based X-ray microscopy with paraffin-mediated contrast enhancement

For three-dimensional observation of unstained bio-specimens using X-ray microscopy with computed tomography (CT), one main problem has been low contrast in X-ray absorption. Here we introduce paraffin-mediated contrast enhancement to visualize biopsy samples of mouse kidney using a laboratory-based...

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Detalles Bibliográficos
Autores principales: Kunishima, Naoki, Hirose, Raita, Takeda, Yoshihiro, Ito, Koichiro, Furuichi, Kengo, Omote, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177607/
https://www.ncbi.nlm.nih.gov/pubmed/35676517
http://dx.doi.org/10.1038/s41598-022-13394-9