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Bcl-3 promotes TNF-induced hepatocyte apoptosis by regulating the deubiquitination of RIP1

Tumor necrosis factor-α (TNF) is described as a main regulator of cell survival and apoptosis in multiple types of cells, including hepatocytes. Dysregulation in TNF-induced apoptosis is associated with many autoimmune diseases and various liver diseases. Here, we demonstrated a crucial role of Bcl-...

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Detalles Bibliográficos
Autores principales: Hu, Yiming, Zhang, Haohao, Xie, Ningxia, Liu, Dandan, Jiang, Yuhang, Liu, Zhi, Ye, Deji, Liu, Sanhong, Chen, Xi, Li, Cuifeng, Wang, Qi, Huang, Xingxu, Liu, Yongzhong, Shi, Yufang, Zhang, Xiaoren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177694/
https://www.ncbi.nlm.nih.gov/pubmed/34853447
http://dx.doi.org/10.1038/s41418-021-00908-7