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Optimal self-assembly of lipid nanoparticles (LNP) in a ring micromixer

Lipid nanoparticles (LNPs) for RNA and DNA delivery have attracted considerable attention for their ability to treat a broad range of diseases and to vectorize mRNA for COVID vaccines. LNPs are produced by mixing biomolecules and lipids, which self-assemble to form the desired structure. In this dom...

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Detalles Bibliográficos
Autores principales: Ripoll, Manon, Martin, Elian, Enot, Mathilde, Robbe, Oscar, Rapisarda, Chiara, Nicolai, Marie-Claire, Deliot, Aurélie, Tabeling, Patrick, Authelin, Jean-René, Nakach, Mostafa, Wils, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177731/
https://www.ncbi.nlm.nih.gov/pubmed/35676394
http://dx.doi.org/10.1038/s41598-022-13112-5