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Insights into Immune Escape During Tumor Evolution and Response to Immunotherapy Using a Rat Model of Breast Cancer

Animal models are critical for the preclinical validation of cancer immunotherapies. Unfortunately, mouse breast cancer models do not faithfully reproduce the molecular subtypes and immune environment of the human disease. In particular, there are no good murine models of estrogen receptor–positive...

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Detalles Bibliográficos
Autores principales: Gil Del Alcazar, Carlos R., Trinh, Anne, Alečković, Maša, Rojas Jimenez, Ernesto, Harper, Nicholas W., Oliphant, Michael U.J., Xie, Shanshan, Krop, Ethan D., Lulseged, Bethlehem, Murphy, Katherine C., Keenan, Tanya E., Van Allen, Eliezer M., Tolaney, Sara M., Freeman, Gordon J., Dillon, Deborah A., Muthuswamy, Senthil K., Polyak, Kornelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177779/
https://www.ncbi.nlm.nih.gov/pubmed/35446942
http://dx.doi.org/10.1158/2326-6066.CIR-21-0804