Allosteric interactions prime androgen receptor dimerization and activation

The androgen receptor (AR) is a nuclear receptor governing gene expression programs required for prostate development and male phenotype maintenance. Advanced prostate cancers display AR hyperactivation and transcriptome expansion, in part, through AR amplification and interaction with oncoprotein c...

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Detalles Bibliográficos
Autores principales: Wasmuth, Elizabeth V., Vanden Broeck, Arnaud, LaClair, Justin R., Hoover, Elizabeth A., Lawrence, Kayla E., Paknejad, Navid, Pappas, Kyrie, Matthies, Doreen, Wang, Biran, Feng, Weiran, Watson, Philip A., Zinder, John C., Karthaus, Wouter R., de la Cruz, M. Jason, Hite, Richard K., Manova-Todorova, Katia, Yu, Zhiheng, Weintraub, Susan T., Klinge, Sebastian, Sawyers, Charles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177810/
https://www.ncbi.nlm.nih.gov/pubmed/35447082
http://dx.doi.org/10.1016/j.molcel.2022.03.035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177810/
https://www.ncbi.nlm.nih.gov/pubmed/35447082
http://dx.doi.org/10.1016/j.molcel.2022.03.035

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