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Jaw1/LRMP increases Ca(2+) influx upon GPCR stimulation with heterogeneous effect on the activity of each ITPR subtype

Ca(2+) influx upon G protein-coupled receptor (GPCR) stimulation is observed as a cytosolic Ca(2+) concentration oscillation crucial to initiating downstream responses including cell proliferation, differentiation, and cell–cell communication. Although Jaw1 is known to interact with inositol 1,4,5-t...

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Detalles Bibliográficos
Autores principales: Okumura, Wataru, Kozono, Takuma, Sato, Hiroyuki, Matsui, Hitomi, Takagi, Tsubasa, Tonozuka, Takashi, Nishikawa, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177832/
https://www.ncbi.nlm.nih.gov/pubmed/35676525
http://dx.doi.org/10.1038/s41598-022-13620-4