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Jaw1/LRMP increases Ca(2+) influx upon GPCR stimulation with heterogeneous effect on the activity of each ITPR subtype
Ca(2+) influx upon G protein-coupled receptor (GPCR) stimulation is observed as a cytosolic Ca(2+) concentration oscillation crucial to initiating downstream responses including cell proliferation, differentiation, and cell–cell communication. Although Jaw1 is known to interact with inositol 1,4,5-t...
Autores principales: | Okumura, Wataru, Kozono, Takuma, Sato, Hiroyuki, Matsui, Hitomi, Takagi, Tsubasa, Tonozuka, Takashi, Nishikawa, Atsushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177832/ https://www.ncbi.nlm.nih.gov/pubmed/35676525 http://dx.doi.org/10.1038/s41598-022-13620-4 |
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