GRHL2 motif is associated with intratumor heterogeneity of cis-regulatory elements in luminal breast cancer

In breast cancer patients, tumor heterogeneity is associated with prognosis and therapeutic response; however, the epigenetic diversity that exists in primary tumors remains unknown. Using a single-cell sequencing assay for transposase-accessible chromatin (scATAC-seq), we obtained the chromatin acc...

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Detalles Bibliográficos
Autores principales: Kumegawa, Kohei, Takahashi, Yoko, Saeki, Sumito, Yang, Liying, Nakadai, Tomoyoshi, Osako, Tomo, Mori, Seiichi, Noda, Tetsuo, Ohno, Shinji, Ueno, Takayuki, Maruyama, Reo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177858/
https://www.ncbi.nlm.nih.gov/pubmed/35676392
http://dx.doi.org/10.1038/s41523-022-00438-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177858/
https://www.ncbi.nlm.nih.gov/pubmed/35676392
http://dx.doi.org/10.1038/s41523-022-00438-6

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