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Brain aging is faithfully modelled in organotypic brain slices and accelerated by prions

Mammalian models are essential for brain aging research. However, the long lifespan and poor amenability to genetic and pharmacological perturbations have hindered the use of mammals for dissecting aging-regulatory molecular networks and discovering new anti-aging interventions. To circumvent these...

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Detalles Bibliográficos
Autores principales: Liu, Yingjun, Senatore, Assunta, Sorce, Silvia, Nuvolone, Mario, Guo, Jingjing, Gümüş, Zeynep H., Aguzzi, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177860/
https://www.ncbi.nlm.nih.gov/pubmed/35676449
http://dx.doi.org/10.1038/s42003-022-03496-5