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Differential Effects of Alarmins on Human and Mouse Basophils

Epithelial-derived alarmins (IL-33, TSLP, and IL-25) play an upstream role in the pathogenesis of asthma. Basophil-derived cytokines are a pivotal component of allergic inflammation. We evaluated the in vitro effects of IL-33, TSLP, and IL-25, alone and in combination with IL-3 on purified periphera...

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Detalles Bibliográficos
Autores principales: Gambardella, Adriana R., Poto, Remo, Tirelli, Valentina, Schroeder, John T., Marone, Gianni, Mattei, Fabrizio, Varricchi, Gilda, Schiavoni, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177950/
https://www.ncbi.nlm.nih.gov/pubmed/35693823
http://dx.doi.org/10.3389/fimmu.2022.894163