Inducible directed evolution of complex phenotypes in bacteria

Directed evolution is a powerful method for engineering biology in the absence of detailed sequence-function relationships. To enable directed evolution of complex phenotypes encoded by multigene pathways, we require large library sizes for DNA sequences >5–10 kb in length, elimination of genomic...

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Detalles Bibliográficos
Autores principales: Al’Abri, Ibrahim S, Haller, Daniel J, Li, Zidan, Crook, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177967/
https://www.ncbi.nlm.nih.gov/pubmed/35150576
http://dx.doi.org/10.1093/nar/gkac094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177967/
https://www.ncbi.nlm.nih.gov/pubmed/35150576
http://dx.doi.org/10.1093/nar/gkac094

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