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Inducible directed evolution of complex phenotypes in bacteria
Directed evolution is a powerful method for engineering biology in the absence of detailed sequence-function relationships. To enable directed evolution of complex phenotypes encoded by multigene pathways, we require large library sizes for DNA sequences >5–10 kb in length, elimination of genomic...
Autores principales: | Al’Abri, Ibrahim S, Haller, Daniel J, Li, Zidan, Crook, Nathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177967/ https://www.ncbi.nlm.nih.gov/pubmed/35150576 http://dx.doi.org/10.1093/nar/gkac094 |
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