Intra-axonal translation of Khsrp mRNA slows axon regeneration by destabilizing localized mRNAs

Axonally synthesized proteins support nerve regeneration through retrograde signaling and local growth mechanisms. RNA binding proteins (RBP) are needed for this and other aspects of post-transcriptional regulation of neuronal mRNAs, but only a limited number of axonal RBPs are known. We used target...

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Detalles Bibliográficos
Autores principales: Patel, Priyanka, Buchanan, Courtney N, Zdradzinski, Matthew D, Sahoo, Pabitra K, Kar, Amar N, Lee, Seung Joon, Vaughn, Lauren S, Urisman, Anatoly, Oses-Prieto, Juan, Dell’Orco, Michela, Cassidy, Devon E, Costa, Irene Dalla, Miller, Sharmina, Thames, Elizabeth, Smith, Terika P, Burlingame, Alma L, Perrone-Bizzozero, Nora, Twiss, Jeffery L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177972/
https://www.ncbi.nlm.nih.gov/pubmed/35556128
http://dx.doi.org/10.1093/nar/gkac337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177972/
https://www.ncbi.nlm.nih.gov/pubmed/35556128
http://dx.doi.org/10.1093/nar/gkac337

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