Hormone-controlled cooperative binding of transcription factors drives synergistic induction of fasting-regulated genes

During fasting, hepatocytes produce glucose in response to hormonal signals. Glucagon and glucocorticoids are principal fasting hormones that cooperate in regulating glucose production via gluconeogenesis. However, how these hormone signals are integrated and interpreted to a biological output is un...

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Detalles Bibliográficos
Autores principales: Goldberg, Dana, Charni-Natan, Meital, Buchshtab, Nufar, Bar-Shimon, Meirav, Goldstein, Ido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177981/
https://www.ncbi.nlm.nih.gov/pubmed/35556130
http://dx.doi.org/10.1093/nar/gkac358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177981/
https://www.ncbi.nlm.nih.gov/pubmed/35556130
http://dx.doi.org/10.1093/nar/gkac358

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