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Hormone-controlled cooperative binding of transcription factors drives synergistic induction of fasting-regulated genes
During fasting, hepatocytes produce glucose in response to hormonal signals. Glucagon and glucocorticoids are principal fasting hormones that cooperate in regulating glucose production via gluconeogenesis. However, how these hormone signals are integrated and interpreted to a biological output is un...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177981/ https://www.ncbi.nlm.nih.gov/pubmed/35556130 http://dx.doi.org/10.1093/nar/gkac358 |