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Catchet-MS identifies IKZF1-targeting thalidomide analogues as novel HIV-1 latency reversal agents

A major pharmacological strategy toward HIV cure aims to reverse latency in infected cells as a first step leading to their elimination. While the unbiased identification of molecular targets physically associated with the latent HIV-1 provirus would be highly valuable to unravel the molecular deter...

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Detalles Bibliográficos
Autores principales: Ne, Enrico, Crespo, Raquel, Izquierdo-Lara, Ray, Rao, Shringar, Koçer, Selin, Górska, Alicja, van Staveren, Thomas, Kan, Tsung Wai, van de Vijver, David, Dekkers, Dick, Rokx, Casper, Moulos, Panagiotis, Hatzis, Pantelis, Palstra, Robert-Jan, Demmers, Jeroen, Mahmoudi, Tokameh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177988/
https://www.ncbi.nlm.nih.gov/pubmed/35640596
http://dx.doi.org/10.1093/nar/gkac407