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The Role of GLI in the Regulation of Hepatic Epithelial–Mesenchymal Transition in Biliary Atresia

OBJECTIVE: To study the regulatory role of GLI1/GLI2, a nuclear transcription factor of the Sonic hedgehog (Shh) signaling pathway, in epithelial–mesenchymal transition (EMT) related to hepatic fibrosis in patients with biliary atresia (BA). METHODS: The messenger RNA (mRNA) and protein expression l...

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Detalles Bibliográficos
Autores principales: Siyu, Pu, Junxiang, Wang, Qi, Wang, Yimao, Zhang, Shuguang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178093/
https://www.ncbi.nlm.nih.gov/pubmed/35692978
http://dx.doi.org/10.3389/fped.2022.861826