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Mechanosurveillance: Tiptoeing T Cells

Efficient scanning of tissue that T cells encounter during their migratory life is pivotal to protective adaptive immunity. In fact, T cells can detect even a single antigenic peptide/MHC complex (pMHC) among thousands of structurally similar yet non-stimulatory endogenous pMHCs on the surface of an...

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Detalles Bibliográficos
Autores principales: Göhring, Janett, Schrangl, Lukas, Schütz, Gerhard J., Huppa, Johannes B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178122/
https://www.ncbi.nlm.nih.gov/pubmed/35693808
http://dx.doi.org/10.3389/fimmu.2022.886328