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Investigation of the Potential Mechanisms Underlying Nuclear F-Actin Organization in Ovarian Cancer Cells by High-Throughput Screening in Combination With Deep Learning

Increasing evidence supports the notion that filamentous actin (F-actin) and globular actin exist in the nuclei of somatic cells, and are involved in chromatin remodeling, gene transcription regulation and DNA damage repair. However, the underlying mechanisms of how nuclear F-actin are polymerized i...

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Detalles Bibliográficos
Autores principales: Wu, Wei, Xing, Xiaoxia, Wang, Mingyang, Feng, Yinzhou, Wietek, Nina, Chong, Kay, El-Sahhar, Salma, Ahmed, Ahmed Ashour, Zang, Rongyu, Zheng, Yiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178185/
https://www.ncbi.nlm.nih.gov/pubmed/35693931
http://dx.doi.org/10.3389/fcell.2022.869531