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Functional and Phenotypic Diversity of Microglia: Implication for Microglia-Based Therapies for Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disease and is closely associated with the accumulation of β-amyloid (Aβ) and neurofibrillary tangles (NFTs). Apart from Aβ and NFT pathologies, AD patients also exhibit a widespread microglial activation in various brain regions with eleva...

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Detalles Bibliográficos
Autores principales: Xu, Yi-Jun, Au, Ngan Pan Bennett, Ma, Chi Him Eddie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178186/
https://www.ncbi.nlm.nih.gov/pubmed/35693341
http://dx.doi.org/10.3389/fnagi.2022.896852