Cargando…

Functional and Phenotypic Diversity of Microglia: Implication for Microglia-Based Therapies for Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disease and is closely associated with the accumulation of β-amyloid (Aβ) and neurofibrillary tangles (NFTs). Apart from Aβ and NFT pathologies, AD patients also exhibit a widespread microglial activation in various brain regions with eleva...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Yi-Jun, Au, Ngan Pan Bennett, Ma, Chi Him Eddie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Aging Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178186/ https://www.ncbi.nlm.nih.gov/pubmed/35693341 http://dx.doi.org/10.3389/fnagi.2022.896852

Ejemplares similares

Recent Advances in the Study of Bipolar/Rod-Shaped Microglia and their Roles in Neurodegeneration
por: Au, Ngan Pan Bennett, et al.
Publicado: (2017)

Neuroinflammation, Microglia and Implications for Retinal Ganglion Cell Survival and Axon Regeneration in Traumatic Optic Neuropathy
por: Au, Ngan Pan Bennett, et al.
Publicado: (2022)

Contribution of “Genuine Microglia” to Alzheimer's Disease Pathology
por: Hashioka, Sadayuki, et al.
Publicado: (2022)

Microglia Polarization in Alzheimer’s Disease: Mechanisms and a Potential Therapeutic Target
por: Wang, Qinqin, et al.
Publicado: (2021)

Bipolar/rod-shaped microglia are proliferating microglia with distinct M1/M2 phenotypes
por: Tam, Wing Yip, et al.
Publicado: (2014)

The Role of Microglia in Alzheimer’s Disease From the Perspective of Immune Inflammation and Iron Metabolism
por: Long, Hui-Zhi, et al.
Publicado: (2022)

Editorial: Expert opinions on the relationship between microglia, glia, and Alzheimer's disease: 2022
por: Gomez-Arboledas, Angela, et al.
Publicado: (2023)

Editorial: The role of microglia in the pathogenesis of neurodegenerative diseases
por: Qin, Qi, et al.
Publicado: (2023)

Emerging Alzheimer’s disease therapeutics: promising insights from lipid metabolism and microglia-focused interventions
por: Tobeh, Nour S., et al.
Publicado: (2023)

The Role of Microglia in Perioperative Neuroinflammation and Neurocognitive Disorders
por: Saxena, Sarah, et al.
Publicado: (2021)

The Interplay Between Brain Vascular Calcification and Microglia
por: Maheshwari, Upasana, et al.
Publicado: (2022)

Editorial: Role of microglia autophagy in age-related neurodegenerative diseases
por: Wang, Zihua
Publicado: (2023)

Microglia Polarization From M1 to M2 in Neurodegenerative Diseases
por: Guo, Shenrui, et al.
Publicado: (2022)

Microglia-Derived Microvesicles Affect Microglia Phenotype in Glioma
por: Grimaldi, Alfonso, et al.
Publicado: (2019)

Platelet Activating Factor Receptor Exaggerates Microglia-Mediated Microenvironment by IL10-STAT3 Signaling: A Novel Potential Biomarker and Target for Diagnosis and Treatment of Alzheimer’s Disease
por: Liu, Junxiu, et al.
Publicado: (2022)

Aging Microglia—Phenotypes, Functions and Implications for Age-Related Neurodegenerative Diseases
por: Spittau, Björn
Publicado: (2017)

Knowledge domains and emerging trends of microglia research from 2002 to 2021: A bibliometric analysis and visualization study
por: Liu, Guangjie, et al.
Publicado: (2023)

The Functions and Phenotypes of Microglia in Alzheimer’s Disease
por: Fujikawa, Risako, et al.
Publicado: (2023)

Synapses, Microglia, and Lipids in Alzheimer’s Disease
por: Paasila, Patrick J., et al.
Publicado: (2022)

Microglia and Astrocytes in Alzheimer's Disease: Implications for Therapy
por: Fakhoury, Marc
Publicado: (2018)

Functional diversity of microglia – how heterogeneous are they to begin with?
por: Hanisch, Uwe-Karsten
Publicado: (2013)

Microglia in Alzheimer’s disease: pathogenesis, mechanisms, and therapeutic potentials
por: Miao, Jifei, et al.
Publicado: (2023)

Microglia in Alzheimer’s Disease: Activated, Dysfunctional or Degenerative
por: Navarro, Victoria, et al.
Publicado: (2018)

Mitochondrial Dysfunction and Alzheimer’s Disease: Role of Microglia
por: Agrawal, Ishan, et al.
Publicado: (2020)

Pharmacological Modulation of Functional Phenotypes of Microglia in Neurodegenerative Diseases
por: Song, Gyun Jee, et al.
Publicado: (2017)

Emerging Roles of Microglia in Neuro-vascular Unit: Implications of Microglia-Neurons Interactions
por: Ding, Zhe, et al.
Publicado: (2021)

The dual face of microglia (M1/M2) as a potential target in the protective effect of nutraceuticals against neurodegenerative diseases
por: Darwish, Samar F., et al.
Publicado: (2023)

Editorial: Systemic implications of Alzheimer's disease
por: Cortes, Constanza J., et al.
Publicado: (2023)

Microglia in Health and Disease: The Strength to Be Diverse and Reactive
por: Uriarte Huarte, Oihane, et al.
Publicado: (2021)

Alzheimer's Disease: The Role of Microglia in Brain Homeostasis and Proteopathy
por: Clayton, Kevin A., et al.
Publicado: (2017)

TREM2-Dependent Effects on Microglia in Alzheimer’s Disease
por: Zhou, Yingyue, et al.
Publicado: (2018)

Microglia in Alzheimer's Disease: A Role for Ion Channels
por: Thei, Laura, et al.
Publicado: (2018)

Microglia and Wnt Pathways: Prospects for Inflammation in Alzheimer’s Disease
por: Yang, Yunying, et al.
Publicado: (2020)

The Role of Microglia in Prion Diseases: A Paradigm of Functional Diversity
por: Obst, Juliane, et al.
Publicado: (2017)

The role of ADAM10 in astrocytes: Implications for Alzheimer’s disease
por: Elsworthy, Richard J., et al.
Publicado: (2022)

Aged Microglia in Neurodegenerative Diseases: Microglia Lifespan and Culture Methods
por: Yoo, Hyun-Jung, et al.
Publicado: (2022)

Microglia and Microglia-Like Cells: Similar but Different
por: Cuadros, Miguel A., et al.
Publicado: (2022)

The Role of Microglia in Retinal Neurodegeneration: Alzheimer's Disease, Parkinson, and Glaucoma
por: Ramirez, Ana I., et al.
Publicado: (2017)

Microglia in Alzheimer Disease: Well-Known Targets and New Opportunities
por: Hemonnot, Anne-Laure, et al.
Publicado: (2019)

Microglia and Cholesterol Handling: Implications for Alzheimer’s Disease
por: Muñoz Herrera, Oscar M., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_53nt6v8p1elkgojnclnedt3h69