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HA/CD44 Regulates the T Helper 1 Cells Differentiation by Activating Annexin A1/Akt/mTOR Signaling to Drive the Pathogenesis of EAP

CD44 partcipates in multiple inflammatory reactions. Here, we aimed to investigate the role of CD44 and the ligand, hyaluronan (HA), on chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) pathogenesis. We found that CD44 was universally expressed in CD4(+) lymphocytes in the peripheral blood...

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Detalles Bibliográficos
Autores principales: Chen, Jing, Meng, Jialin, Li, Xiaoling, Li, Xiao, Liu, Yi, Jin, Chen, Zhang, Li, Hao, Zongyao, Chen, Xianguo, Zhang, Meng, Liang, Chaozhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178196/
https://www.ncbi.nlm.nih.gov/pubmed/35693826
http://dx.doi.org/10.3389/fimmu.2022.875412