PROTACs: great opportunities for academia and industry (an update from 2020 to 2021)

PROteolysis TArgeting Chimeras (PROTACs) technology is a new protein-degradation strategy that has emerged in recent years. It uses bifunctional small molecules to induce the ubiquitination and degradation of target proteins through the ubiquitin–proteasome system. PROTACs can not only be used as po...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Ming, Cao, Chaoguo, Ni, Zhihao, Liu, Yongbo, Song, Peilu, Hao, Shuang, He, Yuna, Sun, Xiuyun, Rao, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178337/
https://www.ncbi.nlm.nih.gov/pubmed/35680848
http://dx.doi.org/10.1038/s41392-022-00999-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178337/
https://www.ncbi.nlm.nih.gov/pubmed/35680848
http://dx.doi.org/10.1038/s41392-022-00999-9

Ejemplares similares