Mitochondrial uncoupling attenuates sarcopenic obesity by enhancing skeletal muscle mitophagy and quality control

BACKGROUND: Sarcopenic obesity is a highly prevalent disease with poor survival and ineffective medical interventions. Mitochondrial dysfunction is purported to be central in the pathogenesis of sarcopenic obesity by impairing both organelle biogenesis and quality control. We have previously identif...

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Detalles Bibliográficos
Autores principales: Dantas, Wagner S., Zunica, Elizabeth R.M., Heintz, Elizabeth C., Vandanmagsar, Bolormaa, Floyd, Z. Elizabeth, Yu, Yongmei, Fujioka, Hisashi, Hoppel, Charles L., Belmont, Kathryn P., Axelrod, Christopher L., Kirwan, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178352/
https://www.ncbi.nlm.nih.gov/pubmed/35304976
http://dx.doi.org/10.1002/jcsm.12982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178352/
https://www.ncbi.nlm.nih.gov/pubmed/35304976
http://dx.doi.org/10.1002/jcsm.12982

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