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Inhibition of epidermal growth factor receptor suppresses parathyroid hormone‐related protein expression in tumours and ameliorates cancer‐associated cachexia

BACKGROUND: Lung cancer is the primary cause of cancer deaths worldwide. Activation of epidermal growth factor receptor (EGFR) leads to lung cancer progression and poor prognosis while involuntary weight loss remains a major problem. Tumour‐derived parathyroid hormone‐related protein (PTHrP) emerged...

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Detalles Bibliográficos
Autores principales: Weber, Bahar Zehra Camurdanoglu, Agca, Samet, Domaniku, Aylin, Bilgic, Sevval Nur, Arabaci, Dilsad H., Kir, Serkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178359/
https://www.ncbi.nlm.nih.gov/pubmed/35373517
http://dx.doi.org/10.1002/jcsm.12985