Nicotinamide‐N‐methyltransferase is a promising metabolic drug target for primary and metastatic clear cell renal cell carcinoma

BACKGROUND: The metabolic enzyme nicotinamide‐N‐methyltransferase (NNMT) is highly expressed in various cancer entities, suggesting tumour‐promoting functions. We systematically investigated NNMT expression and its metabolic interactions in clear cell renal cell carcinoma (ccRCC), a prominent RCC su...

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Detalles Bibliográficos
Autores principales: Reustle, Anna, Menig, Lena‐Sophie, Leuthold, Patrick, Hofmann, Ute, Stühler, Viktoria, Schmees, Christian, Becker, Michael, Haag, Mathias, Klumpp, Verena, Winter, Stefan, Büttner, Florian A., Rausch, Steffen, Hennenlotter, Jörg, Fend, Falko, Scharpf, Marcus, Stenzl, Arnulf, Bedke, Jens, Schwab, Matthias, Schaeffeler, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178377/
https://www.ncbi.nlm.nih.gov/pubmed/35678045
http://dx.doi.org/10.1002/ctm2.883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178377/
https://www.ncbi.nlm.nih.gov/pubmed/35678045
http://dx.doi.org/10.1002/ctm2.883

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