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Single‐cell RNA sequencing reveals the characteristics of cerebrospinal fluid tumour environment in breast cancer and lung cancer leptomeningeal metastases

Leptomeningeal metastases (LM) occur in patients with breast cancer (BC) and lung cancer (LC) showing exceptionally poor prognosis. The cerebrospinal fluid (CSF) tumour microenvironment (TME) of LM patients is not well defined at a single‐cell level. Based on the 10× genomics single‐cell RNA sequenc...

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Detalles Bibliográficos
Autores principales: Ruan, Haoyu, Wang, Zhe, Sun, Ziwei, Wei, Jia, Zhang, Lei, Ju, Huanyu, Wang, Ting, Zhang, Chao, Guan, Ming, Pan, Shiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178395/
https://www.ncbi.nlm.nih.gov/pubmed/35678121
http://dx.doi.org/10.1002/ctm2.885