Modulation of autoimmune diabetes by N-ethyl-N-nitrosourea- induced mutations in non-obese diabetic mice

Genetic association studies of type 1 diabetes (T1D) in humans, and in congenic non-obese diabetic (NOD) mice harboring DNA segments from T1D-resistant mice, face the challenge of assigning causation to specific gene variants among many within loci that affect disease risk. Here, we created random g...

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Detalles Bibliográficos
Autores principales: Chatenoud, Lucienne, Marquet, Cindy, Valette, Fabrice, Scott, Lindsay, Quan, Jiexia, Bu, Chun Hui, Hildebrand, Sara, Moresco, Eva Marie Y., Bach, Jean-François, Beutler, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178510/
https://www.ncbi.nlm.nih.gov/pubmed/35502705
http://dx.doi.org/10.1242/dmm.049484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178510/
https://www.ncbi.nlm.nih.gov/pubmed/35502705
http://dx.doi.org/10.1242/dmm.049484

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