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CXCR4(+) Treg cells control serum IgM levels and natural IgM autoantibody production by B-1 cells in the bone marrow

Regulatory T (Treg) cells represent a specialized lineage of suppressive CD4(+) T cells whose functionality is critically dependent on their ability to migrate to and dwell in the proximity of cells they control. Here we show that continuous expression of the chemokine receptor CXCR4 in Treg cells i...

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Detalles Bibliográficos
Autores principales: Elias, Shlomo, Sharma, Rahul, Schizas, Michael, Valdez, Izabella, Rampersaud, Sham, Park, Sun-Mi, Gonzalez-Figueroa, Paula, Li, Quan-Zhen, Hoyos, Beatrice, Rudensky, Alexander Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178519/
https://www.ncbi.nlm.nih.gov/pubmed/35670812
http://dx.doi.org/10.1084/jem.20220047