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Recombinant ACE2 protein protects against acute lung injury induced by SARS-CoV-2 spike RBD protein

BACKGROUND: SARS-CoV-2 infection leads to acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Both clinical data and animal experiments suggest that the renin–angiotensin system (RAS) is involved in the pathogenesis of SARS-CoV-2-induced ALI. Angiotensin-converting enzyme 2 (ACE2...

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Detalles Bibliográficos
Autores principales: Zhang, Lingbing, Zhang, Yandan, Qin, Xia, Jiang, Xuejun, Zhang, Jun, Mao, Lejiao, Jiang, Ziqi, Jiang, Yu, Liu, Gang, Qiu, Jingfu, Chen, Chengzhi, Qiu, Feng, Zou, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178547/
https://www.ncbi.nlm.nih.gov/pubmed/35681221
http://dx.doi.org/10.1186/s13054-022-04034-9