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Improved Peptide Backbone Fragmentation Is the Primary Advantage of MS-Cleavable Crosslinkers

[Image: see text] Proteome-wide crosslinking mass spectrometry studies have coincided with the advent of mass spectrometry (MS)-cleavable crosslinkers that can reveal the individual masses of the two crosslinked peptides. However, recently, such studies have also been published with noncleavable cro...

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Detalles Bibliográficos
Autores principales: Kolbowski, Lars, Lenz, Swantje, Fischer, Lutz, Sinn, Ludwig R., O’Reilly, Francis J., Rappsilber, Juri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178559/
https://www.ncbi.nlm.nih.gov/pubmed/35613060
http://dx.doi.org/10.1021/acs.analchem.1c05266