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Carnosol inhibits osteoclastogenesis in vivo and in vitro by blocking the RANKL-induced NF-κB signaling pathway

Bone homeostasis is maintained by osteoclast-mediated bone resorption and osteoblast-mediated bone formation. Disruption of bone homeostasis due to excessive osteoclastogenesis or reduced osteogenesis results in various disorders, such as postmenopausal osteoporosis. Receptor activator of NF-κB liga...

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Detalles Bibliográficos
Autores principales: Cai, Pan, Yan, Shichang, Lu, Yan, Zhou, Xiaoxiao, Wang, Xiuhui, Wang, Minghui, Yin, Zhifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178676/
https://www.ncbi.nlm.nih.gov/pubmed/35593299
http://dx.doi.org/10.3892/mmr.2022.12741