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Targeted RNA next generation sequencing analysis of cervical smears can predict the presence of hrHPV-induced cervical lesions

BACKGROUND: Because most cervical cancers are caused by high-risk human papillomaviruses (hrHPVs), cervical cancer prevention programs increasingly employ hrHPV testing as a primary test. The high sensitivity of HPV tests is accompanied by low specificity, resulting in high rates of overdiagnosis an...

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Detalles Bibliográficos
Autores principales: Andralojc, Karolina M., Elmelik, Duaa, Rasing, Menno, Pater, Bernard, Siebers, Albert G., Bekkers, Ruud, Huynen, Martijn A., Bulten, Johan, Loopik, Diede, Melchers, Willem J. G., Leenders, William P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178797/
https://www.ncbi.nlm.nih.gov/pubmed/35676700
http://dx.doi.org/10.1186/s12916-022-02386-1