Cargando…
Complement C3 deficiency alleviates alkylation-induced retinal degeneration in mice
BACKGROUND: It has been found that the extensive use of anticancer drugs containing DNA-alkylating agents not only target cancer cells but also cause retinal inflammation through toxic intermediates. Complement C3 (C3) is a core component of the complement activation pathway, and dysregulation of th...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178834/ https://www.ncbi.nlm.nih.gov/pubmed/35676725 http://dx.doi.org/10.1186/s40662-022-00292-4 |