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Hypertrophic Cardiomyopathy Mutations of Troponin Reveal Details of Striated Muscle Regulation

Striated muscle contraction is inhibited by the actin associated proteins tropomyosin, troponin T, troponin I and troponin C. Binding of Ca(2+) to troponin C relieves this inhibition by changing contacts among the regulatory components and ultimately repositioning tropomyosin on the actin filament c...

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Detalles Bibliográficos
Autores principales: Chalovich, J. M., Zhu, L., Johnson, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178916/
https://www.ncbi.nlm.nih.gov/pubmed/35694406
http://dx.doi.org/10.3389/fphys.2022.902079