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Hypertrophic Cardiomyopathy Mutations of Troponin Reveal Details of Striated Muscle Regulation
Striated muscle contraction is inhibited by the actin associated proteins tropomyosin, troponin T, troponin I and troponin C. Binding of Ca(2+) to troponin C relieves this inhibition by changing contacts among the regulatory components and ultimately repositioning tropomyosin on the actin filament c...
Autores principales: | Chalovich, J. M., Zhu, L., Johnson, D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178916/ https://www.ncbi.nlm.nih.gov/pubmed/35694406 http://dx.doi.org/10.3389/fphys.2022.902079 |
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