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Safety and Efficacy of Combined Intramuscular/Intranasal RAZI-COV PARS Vaccine Candidate Against SARS-CoV-2: A Preclinical Study in Several Animal Models

Several vaccine candidates for COVID-19 have been developed, and few vaccines received emergency approval with an acceptable level of efficacy and safety. We herein report the development of the first recombinant protein-based vaccine in Iran based on the recombinant SARS-CoV-2 spike protein in its...

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Detalles Bibliográficos
Autores principales: Banihashemi, Seyed Reza, Es-haghi, Ali, Fallah Mehrabadi, Mohammad Hossein, Nofeli, Mojtaba, Mokarram, Ali Rezaei, Ranjbar, Alireza, Salman, Mo, Hajimoradi, Monireh, Razaz, Seyad Hossein, Taghdiri, Maryam, Bagheri, Mohsen, Dadar, Maryam, Hassan, Zuhair Mohammad, Eslampanah, Mohammad, Salehi Najafabadi, Zahra, Lotfi, Mohsen, Khorasani, Akbar, Rahmani, Fereidoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179012/
https://www.ncbi.nlm.nih.gov/pubmed/35693788
http://dx.doi.org/10.3389/fimmu.2022.836745