Secreted Amyloid Precursor Protein Alpha, a Neuroprotective Protein in the Brain Has Widespread Effects on the Transcriptome and Proteome of Human Inducible Pluripotent Stem Cell-Derived Glutamatergic Neurons Related to Memory Mechanisms

Secreted amyloid precursor protein alpha (sAPPα) processed from a parent human brain protein, APP, can modulate learning and memory. It has potential for development as a therapy preventing, delaying, or even reversing Alzheimer’s disease. In this study a comprehensive analysis to understand how it...

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Detalles Bibliográficos
Autores principales: Peppercorn, Katie, Kleffmann, Torsten, Jones, Owen, Hughes, Stephanie, Tate, Warren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179159/
https://www.ncbi.nlm.nih.gov/pubmed/35692428
http://dx.doi.org/10.3389/fnins.2022.858524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179159/
https://www.ncbi.nlm.nih.gov/pubmed/35692428
http://dx.doi.org/10.3389/fnins.2022.858524

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