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Pilot Trial of Arginine Deprivation Plus Nivolumab and Ipilimumab in Patients with Metastatic Uveal Melanoma

SIMPLE SUMMARY: Uveal melanoma is a rare subtype of malignant melanoma. It is known to rapidly metastasize, with the liver being the most frequently affected organ. Due to differences from melanoma arising in the skin, such as a lower number of mutations, it responds poorly to immune checkpoint bloc...

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Detalles Bibliográficos
Autores principales: Kraehenbuehl, Lukas, Holland, Aliya, Armstrong, Emma, O’Shea, Sirinya, Mangarin, Levi, Chekalil, Sara, Johnston, Amanda, Bomalaski, John S., Erinjeri, Joseph P., Barker, Christopher A., Francis, Jasmine H., Wolchok, Jedd D., Merghoub, Taha, Shoushtari, Alexander N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179243/
https://www.ncbi.nlm.nih.gov/pubmed/35681616
http://dx.doi.org/10.3390/cancers14112638