Shiga Toxin 2 Triggers C3a-Dependent Glomerular and Tubular Injury through Mitochondrial Dysfunction in Hemolytic Uremic Syndrome

Shiga toxin (Stx)-producing Escherichia coli is the predominant offending agent of post-diarrheal hemolytic uremic syndrome (HUS), a rare disorder of microvascular thrombosis and acute kidney injury possibly leading to long-term renal sequelae. We previously showed that C3a has a critical role in th...

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Detalles Bibliográficos
Autores principales: Buelli, Simona, Locatelli, Monica, Carminati, Claudia Elisa, Corna, Daniela, Cerullo, Domenico, Imberti, Barbara, Perico, Luca, Brigotti, Maurizio, Abbate, Mauro, Zoja, Carlamaria, Benigni, Ariela, Remuzzi, Giuseppe, Morigi, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179250/
https://www.ncbi.nlm.nih.gov/pubmed/35681450
http://dx.doi.org/10.3390/cells11111755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179250/
https://www.ncbi.nlm.nih.gov/pubmed/35681450
http://dx.doi.org/10.3390/cells11111755

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