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Across Dimensions: Developing 2D and 3D Human iPSC-Based Models of Fragile X Syndrome

Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability and autism spectrum disorder. FXS is caused by a cytosine-guanine-guanine (CGG) trinucleotide repeat expansion in the untranslated region of the FMR1 gene leading to the functional loss of the gene’s protein produ...

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Detalles Bibliográficos
Autores principales: Lee, Azalea, Xu, Jie, Wen, Zhexing, Jin, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179297/
https://www.ncbi.nlm.nih.gov/pubmed/35681419
http://dx.doi.org/10.3390/cells11111725